February 2008


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Anti Depressants A Waste Of Time

 
 
New research has shown that new generation anti-depressants work no better that placebo dummy pills seized upon evidence that doctors are over prescribing.

 
Campaigners from the Mental Health said that millions of people with depression are not getting sufficient access to talking to therapists due to GP’s being over reliant on prescribing drugs such as Prozac.  

 
It follows a review of clinical trials that found that such drugs had no more effect than a placebo for mildly depressed patients and for most people suffering severe depression.
The study showed that even trials suggesting benefits for severely depressed people did not provide evidence of clear clinical benefit, researchers said.
Dr Tim Kendall, deputy director of the Royal College of Psychiatrists Research Unit, said the findings were “fantastically important”.
A group of experts, led by Professor Irving Kirsch, from the Department of Psychology at the University of Hull, analysed 47 clinical trials using data released under Freedom of Information rules by the US Food and Drug Administration.
The researchers looked at four commonly used anti-depressants and the clinical trials submitted to gain licensing approval. They included anti-depressants regularly prescribed in the UK, including fluoxetine (Prozac), venlafaxine (Efexor) and paroxetine (Seroxat).
They found little evidence of benefit when analysing both unpublished and published data from the drug companies. Furthermore, the seemingly good results for very severely depressed patients came from the fact a patient’s response to the dummy pill decreased rather than any notable increase in their response to antidepressants.
Professor Kirsch said: “The difference in improvement between patients taking placebos and patients taking antidepressants is not very great. This means that depressed people can improve without chemical treatments.”
Alison Cobb, policy officer at mental health charity Mind, said: “This research is a serious challenge to the predominance of drugs in treating depression. Nine out of 10 GPs say they’ve been forced to dish out drugs because they don’t have proper access to talking treatments such as cognitive behavioural therapy, which are recommended as the first-line treatment for mild to moderate depression.”
Anti Depressants A Waste Of Time

 
 
New research has shown that new generation anti-depressants work no better that placebo dummy pills seized upon evidence that doctors are over prescribing.

 
Campaigners from the Mental Health said that millions of people with depression are not getting sufficient access to talking to therapists due to GP’s being over reliant on prescribing drugs such as Prozac.  

 
It follows a review of clinical trials that found that such drugs had no more effect than a placebo for mildly depressed patients and for most people suffering severe depression.
The study showed that even trials suggesting benefits for severely depressed people did not provide evidence of clear clinical benefit, researchers said.
Dr Tim Kendall, deputy director of the Royal College of Psychiatrists Research Unit, said the findings were “fantastically important”.
A group of experts, led by Professor Irving Kirsch, from the Department of Psychology at the University of Hull, analysed 47 clinical trials using data released under Freedom of Information rules by the US Food and Drug Administration.
The researchers looked at four commonly used anti-depressants and the clinical trials submitted to gain licensing approval. They included anti-depressants regularly prescribed in the UK, including fluoxetine (Prozac), venlafaxine (Efexor) and paroxetine (Seroxat).
They found little evidence of benefit when analysing both unpublished and published data from the drug companies. Furthermore, the seemingly good results for very severely depressed patients came from the fact a patient’s response to the dummy pill decreased rather than any notable increase in their response to antidepressants.
Professor Kirsch said: “The difference in improvement between patients taking placebos and patients taking antidepressants is not very great. This means that depressed people can improve without chemical treatments.”
Alison Cobb, policy officer at mental health charity Mind, said: “This research is a serious challenge to the predominance of drugs in treating depression. Nine out of 10 GPs say they’ve been forced to dish out drugs because they don’t have proper access to talking treatments such as cognitive behavioural therapy, which are recommended as the first-line treatment for mild to moderate depression.”
Anti Depressants A Waste Of Time

 
 
New research has shown that new generation anti-depressants work no better that placebo dummy pills seized upon evidence that doctors are over prescribing.

 
Campaigners from the Mental Health said that millions of people with depression are not getting sufficient access to talking to therapists due to GP’s being over reliant on prescribing drugs such as Prozac.  

 
It follows a review of clinical trials that found that such drugs had no more effect than a placebo for mildly depressed patients and for most people suffering severe depression.
The study showed that even trials suggesting benefits for severely depressed people did not provide evidence of clear clinical benefit, researchers said.
Dr Tim Kendall, deputy director of the Royal College of Psychiatrists Research Unit, said the findings were “fantastically important”.
A group of experts, led by Professor Irving Kirsch, from the Department of Psychology at the University of Hull, analysed 47 clinical trials using data released under Freedom of Information rules by the US Food and Drug Administration.
The researchers looked at four commonly used anti-depressants and the clinical trials submitted to gain licensing approval. They included anti-depressants regularly prescribed in the UK, including fluoxetine (Prozac), venlafaxine (Efexor) and paroxetine (Seroxat).
They found little evidence of benefit when analysing both unpublished and published data from the drug companies. Furthermore, the seemingly good results for very severely depressed patients came from the fact a patient’s response to the dummy pill decreased rather than any notable increase in their response to antidepressants.
Professor Kirsch said: “The difference in improvement between patients taking placebos and patients taking antidepressants is not very great. This means that depressed people can improve without chemical treatments.”
Alison Cobb, policy officer at mental health charity Mind, said: “This research is a serious challenge to the predominance of drugs in treating depression. Nine out of 10 GPs say they’ve been forced to dish out drugs because they don’t have proper access to talking treatments such as cognitive behavioural therapy, which are recommended as the first-line treatment for mild to moderate depression.”
Womens Clothing

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ulrika johnson fashion

Ulrika Johnson has found herself a new gladiator, she asks would you like to come dine with me (sorry photo cropped for regulations, he has nice gold skin tight hotpants on)

ozzy osbourne fashion

Ozzy has taken a break from the school of rock, well yu cant blame him as he is a guitar hero, I am not sure about his ghost rider, I guess its a boy girl thing

billie piper fashion

Billie Piper leaves the canter-beret tales behind to join the ruby in the smoke, looks like she has fallen into the spirit trap

little richard fashion

Little Richard wants to get up close and personal as he is dressed for las vegas let the festival express commence in hollywood land

bill clinton fashion

Quick shine a light at the end of the line says Clinton, this is the swing state and Im the rock and roll president

lyndsey lohan fashion

Lindsey’s Smoke-han, are there any poor things out there who dare to love me

lindsey lohan fashion

Guess its just my luck says Lindsey, she can enter this in to the princess diaries, she obviosly did not leave her royal engagement before midnight if only all transport could be shrunk from life size.

vinnie jones fashion

Vinnie held on for tooth and nail but the heavy midnight meat train just could not hold out, it takes strenth and honour to grasp the riddle

jade goody fashion

Jade has brought herself a goody, what is it a postage stamp, please dont use it to do a dance workout

verne troyer fashion
Verne Troyer shows us how to griphook the goblin before he makes a run for the money, he really is a jack of all trades

Jackets & Coats

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Matthew McConaughey fashion

Matthew McConaughey has a fatal contradiction as he looks dazed and confused while having his hair done, this aint no fools gold

rhys ifans fashion

Rhys Ifans looks like the undertaker in that coat, rather than just be a Mr nobody he is practising to be a number for the restraint of beasts.

kevin costner fashion

Kevin Costner is in open range of getting the explorers club swing vote, rumour has it that it is 3000 miles to graceland, but he does it for the love of the game.

ziggy fashion

Its not Ziggy thats letting one go, as he holds his breath from  the down wind behind him

liv tyler fashion

Liv Tyler can’t hardly wait to get a new face into her dads band, maybe they can play one night at McCools, steve says as long as he doesnt reign over me

tara reid fashion
Tara Reid has jumped back into the devils pond and has hitched herself on the ol cigars, quick get her scrubs and put her in quarantine

britney spears fashion

Britney finds a room thats accessible with out  padding, we hope she had a good rest

sienna miller fashion

Sienna supports her new clothing range to stop you from Bijon Fris-ing who know a dog would make a great shrug

nicole richie
Nicole Richie copies Paris in pillow talk, its a crying talking pillow walking simple life doll, lets hope she also has some good american dreams

Womens Clothing

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ziggy fashion

Ziggy is seen taken Chanelle for a walk, wait a minute its a different pouch, must be the hair cut

uma thurman fashion

Uma Turmans paycheck must not have cleared as she tries to be cool in her prime fashion statement carriage

sienna miller fashion

Sienna Miller practises her hippy hippy shake after someone said shes A Woman of No Importance so she tried out her G I Joe moves on them

matthew perry fashion

Matthew Perry reflects on what kind of day has it been as he awaits calls from the birds of america, guess no one has been in contact yet

kate moss fashion

Kate Moss stares out through a window, so does she want us to read between the lines, guess she is waiting for Pete.

courtney love fashion

Cup if tea and a slice of cake Coutney, Ms love spotted a little wurzle for wear.

christina aguilera fashion

Christina has a Moulin Rouge full of chewing gum, although thats green top looks like a tissue you can not put your gum into it.

amy winehouse fashion

Oh My God Amy Whitehouse is finished in make up for the auditions of Janice from friends if she doesnt get it she could try for Cats.

Clubwear

angie diary project catwalk

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Project Catwalk Angie Diary TOP SECRET - DO NOT ENTER!!! WEEK ONE DAY 1
Nervous, excited, scared- hate the morning of endless introductions as felt like being eaten alive!
Absolutely thrilled we are meeting Kelly Osborne. Felt completely in my element when it came to model choosing and love my girl Jo. King on the cake was when Zandra Rhodes walked in to discuss our challenge and talk design. She is one of my icons and I couldn’t clap hard enough at meeting her. Felt empowered this evening back at house. DAY 2
1st project catwalk today-horrible twist- we had to choose three items of clothing from a designated wardrobe. Everyone was shocked and gobsmacked and even upset at the prospect of losing some clothes. I was just shocked at everyone being shocked, as all I could think of was who’s wardrobe would I get to chose from- as in garment. I hope there are volumes of bright colours. Unfortunately not my style but shall make best of it. Worked hard in the studio. 

DAY 3
Very, very busy in the studio. Ben came in to see each designer and mentor us. Mine was a “dog’s dinner”. I take this with a pinch of salt and respect his work in regards to his advice and comments. Charmed that I might not have enough time as the day was full of very conflicting moments between people and then there was also the “I don’t know what a pattern block is” saga. By tonight I’d got done my Dress  well enough to fit on beautiful model Jo in the morning. 
DAY 4
Absolutely brilliant day! I couldn’t wait to fit my dress on Jo and she looked gorgeous! I finished my work at the studio what seemed like hours before others. Couldn’t believe how well I timed myself. Getting to the catwalk was nerve-wracking- I started to feel sick when it came to light that my model was almost the last to be ready with hair and make up. 

Once on the catwalk, I thought, I would faint several times and had to tell myself to keep it together. Announcing that I was in the top four was just brilliant and I felt so incredibly proud. In a way glad Ross won as I am a terrible winner and a terrible loser. It’s made me pumped up to work even harder on the next challenge and beat Ross. Such a brilliant, proud day! DAY 5
Last night we let our hair down for a top alcohol fuelled evening in a bar and pub! Stayed up till 5am watching movies. Felt sick all day Sunday, but ok after seeing Transformers movie. Katy and I exchanged popcorn at the cinema and she lovingly left me some in my bed. Really pumped up for the next challenge-keep telling Ross I’m going to beat him this week! 
WEEK 2 

Day 1
Went to Soho Hotel today to meet Nancy, our celebrity client. Had 15 minutes to stretch design then 3 minutes to pitch. Could mainly think of Kiera Knightly as she walked by in a hall before we saw collection of Nancy’s clothes. 
Day 2
Work day- my design did not get picked by Nancy so understandably upset inside. Katy chose me her assistant- was happy as we get on really, really well. I had to do the fabric shopping by the time it was over I was over not having my design picked. Very hard working day. 
Day 3
Very busy work day. Worked exceptionally hard with Katy. Non-stop sewing all day. Just tired. 
Day 4
Catwalk day. Absolutely mind blowing scary as I was in the lower 6. Everyone in top 4 last week were in top six except for me so very concerned. Knew I wasn’t going home as I worked very hard this week on someone else’s design so not my fault to be in the bottom six. I remained in my professional mode throughout whole horrible ordeal so really proud of myself. No way will I be in bottom again. 

Day 5
Given phones as a treat. Feel absolutely sick as had a little too much to drink last night and threw up at 2am. Kelly came over to hang out which was very cool. Lying in park having some sun and quick time. Telling myself to be strong and not to worry about just scrapping through to this week. Will show judges the real me next week challenge. 
Angie’s Diary WEEK 3 Day 1
3RD challenge today, woke up very nervous today. I had a cry, as I’m missing my kids terribly. Driven to a fancy Hotel, met Gary from Macintosh, told we were making a Mac then told I had to do menswear. Hated the project, hate menswear. Sh***y fabric selection. Want to cry more. 

Day 2
Make day-hideous men’s Mac. Very, very homesick thinking what the hell, what the hell, worked hard, enjoyed the sewing as therapy. Had positive and negative moments - HATE MENSWEAR!! 
Day 3
More twisting of the knife today had to finish stupid men’s Mac this morning then spent the afternoon pitching my garments to Gary and two independent players, I was picked as first to pitch. Nervous as hell! Hated, hated, hated trying to sell stupid a Mac. Debbie came back to café after her pitch excited and blabbing. I decided if the camera went onto me for a reaction to Debbie that instead of speaking, I would simply walk out of the café. Sh**y competition. 
Day 4
Today I woke up seriously thinking I would be the one leaving the house after the catwalk. Fortunately, I have 9 lives and I’m still here! Everyone thought Debbie would stay simply for TV and were going to have a riot if I was gone. Love the guys, got so many hugs all round for still being here. Felt really loved. 
Day 5
Fantastic day off! Laid in till 9, Ross made fry up for brunch then spent afternoon in Queensway shopping and bowling. Ross and guys making fantastic roast for dinner. Our house has a great air about it now that Debbie has gone! 

Angie’s Diary WEEK 4  DAY 1
In the morning we were whisked away to Firetrap-cool branded Clothing . We were divided into 3 teams to make a collection for a music festival. I was appointed fabric buying and taken to an ugly, disastrous, fabric shop; which had nothing in it my team wanted. Complete joke. Came back with ridiculous cloth which put me into hysterics for minutes. Jasper praised me, while poor Fionnuala held her head in their hands for a while. Everyone spent the evening laughing at my selection. Hated the fabric buying job. Hideous shop. 
DAY 2
More studio day- Ben came in and said our fabrics were childlike so the meeting started very negative-all to do with fabric, but it did end on a positive note. Ben loved our shapes and all our pieces could interact well. I had a tiny cry in the toilets which cameras didn’t see. Felt very low most of the day as I really felt I had let my team down. Fionnuala bought me back to reality and was a fantastic team leader. Finished everything at studio not knowing what top I was going to make! I looked for the first time at the house and the guys made a lovely red onion risotto and baked lemon fresh for dinner. Yummy. 
DAY 3
Early start this morning- 7.30am at the studio for 3 hours to finish making group ranges. Ben came in to see us with another twist as per usual. We had to paint a backdrop canvas to put in Firetrap’s window at Covent Garden with our models. I considered this a massive sight more, was not on same wave length as my team and struggled to enjoy anything about making a backdrop. Spent the afternoon at Covent Garden having to grab votes from the public with our models as our mannequins! Fantastic fun, absolute high and I didn’t want to leave Project Catwalk!

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