Archive for February, 2008

The Drugs Don’t Work They Just Make You Worse

Anti Depressants A Waste Of Time?


New research has shown that new generation anti-depressants work no better that placebo dummy pills seized upon evidence that doctors are over prescribing.

 
Campaigners from the Mental Health said that millions of people with depression are not getting sufficient access to talking to therapists due to GP’s being over reliant on prescribing drugs such as Prozac.  

 
It follows a review of clinical trials that found that such drugs had no more effect than a placebo for mildly depressed patients and for most people suffering severe depression.
The study showed that even trials suggesting benefits for severely depressed people did not provide evidence of clear clinical benefit, researchers said.
Dr Tim Kendall, deputy director of the Royal College of Psychiatrists Research Unit, said the findings were “fantastically important”.
A group of experts, led by Professor Irving Kirsch, from the Department of Psychology at the University of Hull, analysed 47 clinical trials using data released under Freedom of Information rules by the US Food and Drug Administration.
The researchers looked at four commonly used anti-depressants and the clinical trials submitted to gain licensing approval. They included anti-depressants regularly prescribed in the UK, including fluoxetine (Prozac), venlafaxine (Efexor) and paroxetine (Seroxat).
They found little evidence of benefit when analysing both unpublished and published data from the drug companies. Furthermore, the seemingly good results for very severely depressed patients came from the fact a patient’s response to the dummy pill decreased rather than any notable increase in their response to antidepressants.
Professor Kirsch said: “The difference in improvement between patients taking placebos and patients taking antidepressants is not very great. This means that depressed people can improve without chemical treatments.”
Alison Cobb, policy officer at mental health charity Mind, said: “This research is a serious challenge to the predominance of drugs in treating depression. Nine out of 10 GPs say they’ve been forced to dish out drugs because they don’t have proper access to talking treatments such as cognitive behavioural therapy, which are recommended as the first-line treatment for mild to moderate depression.”
Anti Depressants A Waste Of Time 
New research has shown that new generation anti-depressants work no better that placebo dummy pills seized upon evidence that doctors are over prescribing.

 
Campaigners from the Mental Health said that millions of people with depression are not getting sufficient access to talking to therapists due to GP’s being over reliant on prescribing drugs such as Prozac.  

 
It follows a review of clinical trials that found that such drugs had no more effect than a placebo for mildly depressed patients and for most people suffering severe depression.
The study showed that even trials suggesting benefits for severely depressed people did not provide evidence of clear clinical benefit, researchers said.
Dr Tim Kendall, deputy director of the Royal College of Psychiatrists Research Unit, said the findings were “fantastically important”.
A group of experts, led by Professor Irving Kirsch, from the Department of Psychology at the University of Hull, analysed 47 clinical trials using data released under Freedom of Information rules by the US Food and Drug Administration.
The researchers looked at four commonly used anti-depressants and the clinical trials submitted to gain licensing approval. They included anti-depressants regularly prescribed in the UK, including fluoxetine (Prozac), venlafaxine (Efexor) and paroxetine (Seroxat).
They found little evidence of benefit when analysing both unpublished and published data from the drug companies. Furthermore, the seemingly good results for very severely depressed patients came from the fact a patient’s response to the dummy pill decreased rather than any notable increase in their response to antidepressants.
Professor Kirsch said: “The difference in improvement between patients taking placebos and patients taking antidepressants is not very great. This means that depressed people can improve without chemical treatments.”
Alison Cobb, policy officer at mental health charity Mind, said: “This research is a serious challenge to the predominance of drugs in treating depression. Nine out of 10 GPs say they’ve been forced to dish out drugs because they don’t have proper access to talking treatments such as cognitive behavioural therapy, which are recommended as the first-line treatment for mild to moderate depression.”
Anti Depressants A Waste Of Time

  
New research has shown that new generation anti-depressants work no better that placebo dummy pills seized upon evidence that doctors are over prescribing.

 
Campaigners from the Mental Health said that millions of people with depression are not getting sufficient access to talking to therapists due to GP’s being over reliant on prescribing drugs such as Prozac.  

 
It follows a review of clinical trials that found that such drugs had no more effect than a placebo for mildly depressed patients and for most people suffering severe depression.
The study showed that even trials suggesting benefits for severely depressed people did not provide evidence of clear clinical benefit, researchers said.
Dr Tim Kendall, deputy director of the Royal College of Psychiatrists Research Unit, said the findings were “fantastically important”.
A group of experts, led by Professor Irving Kirsch, from the Department of Psychology at the University of Hull, analysed 47 clinical trials using data released under Freedom of Information rules by the US Food and Drug Administration.
The researchers looked at four commonly used anti-depressants and the clinical trials submitted to gain licensing approval. They included anti-depressants regularly prescribed in the UK, including fluoxetine (Prozac), venlafaxine (Efexor) and paroxetine (Seroxat).
They found little evidence of benefit when analysing both unpublished and published data from the drug companies. Furthermore, the seemingly good results for very severely depressed patients came from the fact a patient’s response to the dummy pill decreased rather than any notable increase in their response to antidepressants.
Professor Kirsch said: “The difference in improvement between patients taking placebos and patients taking antidepressants is not very great. This means that depressed people can improve without chemical treatments.”
Alison Cobb, policy officer at mental health charity Mind, said: “This research is a serious challenge to the predominance of drugs in treating depression. Nine out of 10 GPs say they’ve been forced to dish out drugs because they don’t have proper access to talking treatments such as cognitive behavioural therapy, which are recommended as the first-line treatment for mild to moderate depression.”
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Celebrity Snap Shots

ulrika johnson fashion

Ulrika Johnson has found herself a new gladiator, she asks would you like to come dine with me (sorry photo cropped for regulations, he has nice gold skin tight hotpants on)

ozzy osbourne fashion

Ozzy has taken a break from the school of rock, well yu cant blame him as he is a guitar hero, I am not sure about his ghost rider, I guess its a boy girl thing

billie piper fashion

Billie Piper leaves the canter-beret tales behind to join the ruby in the smoke, looks like she has fallen into the spirit trap

little richard fashion

Little Richard wants to get up close and personal as he is dressed for las vegas let the festival express commence in hollywood land

bill clinton fashion

Quick shine a light at the end of the line says Clinton, this is the swing state and Im the rock and roll president

lyndsey lohan fashion

Lindsey’s Smoke-han, are there any poor things out there who dare to love me

lindsey lohan fashion

Guess its just my luck says Lindsey, she can enter this in to the princess diaries, she obviosly did not leave her royal engagement before midnight if only all transport could be shrunk from life size.

vinnie jones fashion

Vinnie held on for tooth and nail but the heavy midnight meat train just could not hold out, it takes strenth and honour to grasp the riddle

jade goody fashion

Jade has brought herself a goody, what is it a postage stamp, please dont use it to do a dance workout

verne troyer fashion
Verne Troyer shows us how to griphook the goblin before he makes a run for the money, he really is a jack of all trades

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Celebrity Clicks

www.j-lou.com

Matthew McConaughey fashion

Matthew McConaughey has a fatal contradiction as he looks dazed and confused while having his hair done, this aint no fools gold

rhys ifans fashion

Rhys Ifans looks like the undertaker in that coat, rather than just be a Mr nobody he is practising to be a number for the restraint of beasts.

kevin costner fashion

Kevin Costner is in open range of getting the explorers club swing vote, rumour has it that it is 3000 miles to graceland, but he does it for the love of the game.

ziggy fashion

Its not Ziggy thats letting one go, as he holds his breath from  the down wind behind him

liv tyler fashion

Liv Tyler can’t hardly wait to get a new face into her dads band, maybe they can play one night at McCools, steve says as long as he doesnt reign over me

tara reid fashion
Tara Reid has jumped back into the devils pond and has hitched herself on the ol cigars, quick get her scrubs and put her in quarantine

britney spears fashion

Britney finds a room thats accessible with out  padding, we hope she had a good rest

sienna miller fashion

Sienna supports her new clothing range to stop you from Bijon Fris-ing who know a dog would make a great shrug

nicole richie
Nicole Richie copies Paris in pillow talk, its a crying talking pillow walking simple life doll, lets hope she also has some good american dreams

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